WASHINGTON — If the Democratic Party has a stronghold on Wall Street, it is JPMorgan Chase.

Its chief executive, Jamie Dimon, is a friend of President Barack Obama's from Chicago, a frequent White House guest and a big Democratic donor. Its vice chairman, William M. Daley, a former Clinton administration Cabinet official and Obama transition adviser, comes from Chicago's Democratic dynasty.

But this year Chase's political action committee is sending the Democrats a pointed message. While it has contributed to some individual Democrats and state organizations, it has rebuffed solicitations from the national Democratic House and Senate campaign committees. Instead, it gave $30,000 to their Republican counterparts.

The shift reflects the hard political edge to the industry's campaign to thwart Obama's proposals for tighter financial regulations.

Just two years after Obama helped his party pull in record Wall Street contributions — $89 million from the securities and investment business, according to the non-partisan Center for Responsive Politics — some of his biggest supporters, like Dimon, have become the industry's chief lobbyists against his regulatory agenda.

Republicans are rushing to capitalize on what they call Wall Street's "buyer's remorse" with the Democrats. And industry executives and lobbyists are warning Democrats that if Obama keeps attacking Wall Street "fat cats," they might fight back by withholding their cash.

"If the president doesn't become a little more balanced and centrist in his approach, then he will likely lose that support," said Kelly S. King, chairman and chief executive of BB&T. King is a board member of the Financial Services Roundtable, which lobbies for the biggest banks, and last month he helped represent the industry at a private dinner at the Treasury Department.

"I understand the public outcry," he said. "We have a 17 percent real unemployment rate, people are hurting, and they want to see punishment. But the political rhetoric just incites more animosity and gets people riled up."

Many Wall Street lobbyists and executives said they, too, were rethinking their giving.

"The expectation in Washington is that 'We can kick you around, and you are still going to give us money,'" said a top official at a major Wall Street firm, speaking on the condition of anonymity for fear of alienating the White House. "We are not going to play that game anymore."