Tom Cruise (Joel): One of Hollywood's most famous names, Cruise, 50, has been nominated for an Oscar three times. He will be seen next in Oblivion, opening April 12, as a court-martialed soldier sent to a distant planet to battle aliens. He's reportedly at work on Mission: Impossible 5.
Rebecca De Mornay (Lana): De Mornay, 53, has acted steadily since her breakout role in Risky Business, including probably her best-known role, as the malevolent nanny in The Hand That Rocks the Cradle (1992). She made news last month when it was announced she would play the Hatfield matriarch, Mary, in NBC's modern update of the legendary feud between the Hatfields and McCoys. Produced by Charlize Theron, the soapy-sounding Hatfields & McCoys takes place in Pittsburgh among the descendants of the Kentucky and West Virginia families.
Joe Pantoliano (Guido): With a long résumé, Pantoliano, 61, is probably best known for playing Ralphie on The Sopranos, which earned him an Emmy for best supporting actor in 2003.
Curtis Armstrong (Miles): Risky Business was the film debut for Armstrong, 59, who went on most notably to play Booger in the Revenge of the Nerds franchise and Bert Viola on TV's Moonlighting. A character actor who has been seen in many, many roles, he's now working on two animated series: as the title character in The Hub's Dan Vs. and as Snot on Fox's American Dad.