The Whitaker Bank inside the Kroger store on Romany Road was robbed Saturday morning.
Lt. Chris Van Brackel said a man walked into the store and handed the teller a note demanding money.
He left with cash and was seen getting into a gold Toyota Camry on Cooper Drive.
The man was white, about 5-foot-6 and 175 pounds. He wore a red baseball cap, yellow-rimmed glasses and a teal button-down shirt.
Anyone with information is asked to call Lexington police or Crime Stoppers.
"People saw this guy and didn't know that he was a bank robber," Van Brackel said.