Two men were charged with burglary late Thursday night after they allegedly broke into Lexington's historic Hunt-Morgan House on Mill Street.
Officers went to the house just before midnight after a burglar alarm went off and the alarm company heard sounds inside the building, police spokeswoman Sherelle Roberts said.
Officers saw two men fleeing the property and detained them, Roberts said.
An inspection of the building indicated that someone had tried to pry open a door and had broken a window, police said.
Clayton Yearta, 32, and Lowell Green, 39, were charged with third-degree burglary and possession of burglar tools.
The Hunt-Morgan House, which now holds a museum, was home to some of Kentucky's most famous residents.
It was built in 1814 by John Wesley Hunt, known as the first millionaire west of the Allegheny Mountains. Later, it was home to John Hunt Morgan, a famed Confederate cavalry commander during the Civil War.
The general's great-grandson, Thomas Hunt Morgan, was born in the house and went on to win a Nobel Prize in 1933 for his research in genetics.