Skip Horine, a businessman who ran unsuccessfully for mayor of Lexington in 1993, is trying again.
Horine, 42, said he filed because "I think I can take care of a lot of the problems we have better than the current candidates."
In the 1993 race, Horine finished last in a three-way primary that saw incumbent Pam Miller grab 80 percent of the vote.
He also ran unsuccessfully for an Urban County Council seat in 1996.
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In an interview Thursday, Horine said that while the mayoral race is non-partisan, he is a Republican and his opponents are Democrats.
He described himself as "a Ronald Reagan Republican, minus the religious right."