Thomas More 48, St. John Fisher 0: Senior wide receiver Tyler Vogelpohl set a single-game school record with 207-yards receiving in the Saints' win. It was the first time Thomas More had shut out an opponent since Nov. 2, 2013.
Centre 63, Hanover 7: Heath Haden passed for three touchdowns while four different Colonels ran for TDs — Amoh Kumengisa and Colin Burnam for two each. Centre capped the night with a 79-yard touchdown run by Trevor Carnell.
Lindsey Wilson 76, Lyon 10: Lindsey Wilson football scored 62 straight points over the final three quarters to sprint away from host Lyon for the second largest point total in program history. Allen Cooks had two punt returns for touchdowns, including one for 92 yards.
Cumberland 33, Georgetown 25: Georgetown fumbled twice in its season-opener, and both were recovered by host Cumberland. The second one was the dagger. Georgetown was driving with 7:57 left when Cumberland recovered Zach Harris' fumble on the Bulldogs' 23-yardline. With a 27-26 lead, Cumberlands rushed for a 72-yard touchdown. A missed point after attempt kept it within seven, but Cumberland's defense stonewalled the Tigers.
James Madison 56, Morehead State 7: Vad Lee threw three touchdowns and ran for another as James Madison rolled over Morehead State. The Eagles' only score came on a 1-yard keeper by Austin Gahafer late in the second quarter. Gahafer had 173 yards passing.
Hampton 35, Kentucky State 20: Ora Johnson found Reginal Harris from 19 yards and ran seven for another score for the Thorobreds. Kyle Jackson had 93 yards rushing and Jermaine Graham had two of Hampton's three interceptions.
Warner (Fla.) 42, Union 21: The host Bulldogs racked up 440 yards in total offense, but they turned the ball over five times, resulting in 21 points for their opponents. "When you have 440 yards in offense and lose, that should never happen. We just turned it over way too much," Coach Zak Willis said. LaVance Anderson, a senior out of Bowling Green, ran for a game-high 132 yards and a touchdown for Union.
Duquesne 47, Kentucky Christian 7: Duquesne rolled up 571 yards offense against Kentucky Christian in Pittsburgh. The lone touchdown for the NAIA Knights came on Robert Powell's 56-yard pass to Tyler Hadynski in the fourth quarter.