Lipscomb took a five-run lead in the sixth inning Wednesday and held on to beat Kentucky 10-8 at Cliff Hagan Stadium, the Cats' second high-scoring loss in as many days.
After falling to Indiana 18-17 in 10 innings on Tuesday, UK gave up all 10 runs through six and committed three errors to drop to 26-23 for the season.
The Cats got another productive game from senior catcher Marcus Nidiffer, who went 2-for-4 with two RBI after his 5-for-7 performance against the Hoosiers. Junior second baseman Chris Bisson also knocked in two runs.
But Lipscomb center fielder Ryan Wilkins harassed UK's freshman starter, Sam Kidd, driving in the first five runs with homers in the first and third innings.
Kidd (1-2) gave up seven runs, six earned, with no strikeouts and hit two batters before sophomore Chase Greene relieved him in the fifth following a lead-off home run.
The Cats rallied in the eighth with three runs, but they left two on base in the ninth.