Jason Seamands, who led Lexington Christian Academy to the Girls' Sweet Sixteen championship in 2007, is stepping down as the Eagles' coach.
Seamands said his "passion for the game isn't as strong as it needs to be" to continue as coach.
Seamands had a seven-year record of 150-65, including two 11th Region titles. He coached LCA's boys for five seasons before taking over the girls' program.
"I'm a little worried I'm going to really, really miss it, and I'm going to think, 'What have I done?'" he said. "I'm also worried I won't miss it.
"But I definitely feel I need a break. My kids are 9 and 8, and I need more time with them and my wife."
While Seamands is leaving on his own terms, Bryan Station Coach Donna Murphy is not. Murphy has been fired after two years with the Defenders.
Bryan Station Athletics Director Chad Luhman said the school wanted to go in "another direction."
Murphy said she felt she had the program on the upswing, but she thought parental involvement impacted the administration's decision.
"I wonder how far we could have gone without the drama," Murphy said.
Murphy, who previously had a 40-18 record in two years (2004-06) at LCA, was 34-26 at Bryan Station, 18-11 this past season.
Murphy said she hopes to work with the Lindsey Wilson College women's program.
"I think (Bryan Station) did me a favor by freeing me up," she said.