No. 7 Holmes and No. 10 Covington Catholic advanced to the 9th Region boys' finals to set up a rematch of last year's region title game that the Bulldogs won in overtime.
Covington Catholic (28-2) knocked off Newport Central Catholic (29-4), third in Dave Cantrall's Rating the State, 51-43 in one of Sunday's semifinal games at Northern Kentucky University.
Nick Rutsatz scored a game-high 20 points and the Colonels went 8-for-8 in the fourth quarter to pull away for the victory.
Covington Catholic shot its free throws well the entire game, going 14-for-15, while Newport Catholic struggled at 5-for-16, including 0-for-5 in the final period.
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In the other 9th Region semifinal, James "Beetle" Bolden scored 18 points to help Holmes (28-5) edge Dixie Heights (24-7) 54-51.
No. 2 Louisville Trinity 62, No. 12 Manual 45 (7th): The Shamrocks advanced to the region title game and will play top-ranked Ballard on Tuesday at Valley.
No. 1 Elizabethtown 73, No. 9 LaRue County 56 (5th): The top-ranked Lady Panthers jumped out to an 18-7 lead and went on to win the region title at Nelson County.
Erin Boley scored 25 points, grabbed eight rebounds and added three steals and two assists for Elizabethtown.
Alexis Brewer had 28 points, and Ivy Brown scored 20 to go with 15 rebounds and four assists for the Lady Hawks.
No. 20 Newport Central Catholic 48, No. 22 Notre Dame (9th): Michaela Ware hit a driving layup as time expired at NKU to send the Thoroughbreds to the Sweet Sixteen.
No. 12 Danville 68, No. 25 Mercer County 58 (12th): Danville earned the first Sweet Sixteen berth in school history with a win at Lincoln County.
Essence Grey scored 22 points for the Lady Admirals.