CINCINNATI — Todd Frazier's long home run gave Mat Latos all the run support he needed, and Latos gave the Cincinnati Reds exactly what they needed to finish off a 10-game homestand in style.
Latos retired the first 10 batters and 15 of the first 16 he faced and mostly spared an overworked bullpen, and the Reds beat the Chicago Cubs 1-0 Wednesday.
"This is what we wanted so bad," Reds Manager Dusty Baker said. "This sets us straight for a couple of days."
With one out in the sixth inning of a scoreless tie, Frazier blasted a 2-1 pitch from Jeff Samardzija 480 feet to straightaway center field to increase his team-leading home run total to six. The homer is the longest at Great American Ball Park this season and the seventh-longest in the facility's 11-year history.
"I was just trying to get a fastball," Frazier said. "I haven't seen too many lately. I got one, and I took advantage of it."
Latos (1-0), the victim of two blown saves among his first four starts this season, allowed four hits and a walk with four strikeouts. Jonathan Broxton replaced Latos with two runners on base and nobody out in the eighth.
Both runners moved up on Cody Ransom's sacrifice bunt, but pinch-hitter Alfonso Soriano struck out and shortstop Zack Cozart went deep behind second base to flag down David DeJesus's grounder and throw him out to end the inning.
"I've been struggling at the plate lately, so to make a play like that makes you feel pretty good," Cozart said.
Cubs Manager Dale Sveum said that's just the way it's been going for the Cubs, who are 1-5 on their current road trip.
"That was an unbelievable play in that situation," he said. "Before that DeJesus hit a foul that missed the line by less than a foot. That's what happens when things aren't going your way."
Aroldis Chapman pitched the ninth for his fourth save. Latos' effort left Cincinnati's starting pitchers with a combined 5-0 record and 1.54 ERA on the homestand.
Samardzija (1-4) had his fourth consecutive loss after beating Pittsburgh in the opener. The right-hander allowed seven hits and three walks with eight strikeouts.
The Reds won eight games in the 10-game homestand.
Reds at Nationals
When: 7:05 p.m.
Pitchers: Reds, Arroyo (2-1); Nationals, Gonzalez (1-1)
TV: FS Ohio Radio: WVLK-FM 101.5