City Barbeque will open a second Lexington restaurant, this time on Harrodsburg Road.
The chain already operates a restaurant at 3292 Richmond Road.
Leda Isenhour, regional marketing manager for the chain, said the new store at 2187 Harrodsburg Road will be 3,000 square feet with an outdoor patio and will seat 80 guests.
City Barbeque will be in front of the University of Kentucky clinic and beside Walgreen's drug store. The UK clinic site used to be the Dillard's on Turfland Mall.
Grand opening for the City Barbeque is set for early to mid-December, Isenhour said. The chain is accepting applications on its Web site, Citybbq.com, under the careers tab.
The chain, which opened its first restaurant in 1999 in Columbus, Ohio, opened on Richmond Road in 2012.
It also has stores in Florence and Highland Heights.