A windchill advisory is in effect for Fayette and surrounding counties until 10 a.m.
The temperature can feel like it is anywhere between 0 and negative 10 degrees depending on the wind, said Angie Lese, a meteorologist with National Weather Service in Louisville.
Temperatures are expected soar to 16 degrees on Thursday, but it will be back down to 0 and possibly colder tonight, she said.
Lexington shelters were expecting an influx of homeless men and women Wednesday night because of an arctic cold front and wind chills.
The Catholic Action Center had 48 people by 9:45 Wednesday night. On a normal night it would have 28 to 35 people. Director Ginny Ramsey expected more by 2 a.m.
The center began staying open 24 hours in October because the slow economy has caused a rise in homelessness. Police and sheriff's deputies were also bringing people to the shelter.
"We are definitely preparing," Hope Center spokeswoman Kim Livesay said. "We're calling in extra staff to help prepare food at the sites." The Hope Center sent overflow to Grace Baptist Church on Loudon and Bryan avenues.
The Salvation Army was at capacity on several recent days, Maj. Debra Ashcraft said. As of Wednesday afternoon, 10 beds for women were empty, but all the family rooms were taken, she said.