The Cardinals (25-7) earned a No. 3 seed and will host the first and second rounds at the KFC Yum Center. Their opener is against Central Arkansas at 2:30 p.m. Friday.
Louisville has won 24 of its last 27 games and finished the season eighth in both major polls.
Atlantic Coast Conference Player of the Year Myisha Hines-Allen leads the Cards in scoring (17.5) and rebounding (8.4), while shooting 54.0 percent from the field. Classmate Mariya Moore is second in scoring (14.0) and first in assists with 142.