Morehead State scored the last 35 points of the game and throttled visiting Campbell 70-28 Saturday.
Five different Morehead State players scored touchdowns after Campbell had pulled within 35-28 early in the third quarter.
The Eagles' 70-point total was their highest since a 73-10 victory over Austin Peay in 2000. Morehead State had exactly 700 yards of offense.
"I thought today was an outstanding effort and performance by our football team," Coach Matt Ballard said. "This shows if you do things right and do things together, the results will come."
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Zach Lewis passed for 339 yards and five touchdowns, and Donte Sawyer caught six passes to set Morehead State's career receptions record. He has 171 catches for 2,091 yards.
Sawyer also returned a kickoff 94 yards for a touchdown with 31 seconds to play in the first half.
The win was Morehead State's first in the Pioneer Football League this season. The Eagles improved to 2-6 overall and 1-4 in the league.
Jacksonville State 38, Murray State 35: Griffin Thomas kicked the game-winning 38-yard field goal midway through the fourth quarter, and host Jacksonville State (5-3, 4-2 Ohio Valley Conference) forced two late turnovers in a win over Murray State (3-5, 2-3).
Murray State had two more chances after the kick, but the Racers failed to convert on a fourth-and-2 at the Jacksonville State 45-yard line, then had a pass intercepted.
Washaun Ealey, a Georgia transfer, rushed for three scores and 146 yards on 37 carries for Jacksonville State.
Lane 28, Kentucky State 14: McKinsley Marbury ran for 90 yards and three touchdowns to go with his 217 yards passing as Lane (4-5) beat host Kentucky State (1-7). Eric Knowlton added 120 yards rushing, including a 46-yard TD run. Justin Williams led KSU with 129 yards on 17 carries.
Thomas More 38, Saint Vincent 3: Host Thomas More held Saint Vincent to 103 yards of offense in the Presidents' Athletic Conference rout. Adam Rauch ran for 92 yards and three touchdowns for Thomas More (5-3, 5-2). Saint Vincent fell to 0-8, 0-6.
Centre 17, Austin 0: Centre (6-2) outgained host Austin 418-160, and its defense forced two turnovers and sacked Austin's Noah Jesko four times. Monte Scotton ran for 89 yards and a touchdown, and Heath Haden had 57 yards rushing and 237 passing.
Virginia-Wise 14, Union 10: Virginia-Wise scored two first-half touchdowns and spoiled Union's homecoming. Rob Brown carried 20 times for 90 yards and a touchdown for Union (3-6, 0-3 Mid-South).