Domonique Hayden, a former standout at Lexington Christian, set two Thomas More school records as the Saints plowed past visiting Westminster 49-6.
Hayden rushed for a single-game record 336 yards and four touchdowns in the rout.
The senior entered the game needing 94 yards to eclipse the Saints' career rushing total of 4,546 yards set by Will Castleberry in the 2000 season. Hayden's performance Saturday afternoon left him at 4,788 yards in his career with at least six games left to play.
"It's a blessing knowing I broke those records, but I'm not really caught up with stats and everything," Hayden said after the win. "I know when I come here on Saturday, I'm playing for my teammates.
"Whatever yards and touchdowns I rack up, that's not of importance. It's about me doing everything I can to help my teammates win."
Hayden scored from 2, 45, 52 and 70 yards for the Saints, ranked 20th in NCAA Division III. He has 748 yards and 12 TDs through four games this season.
Pikeville 22, Cumberlands 7: Seth Millar rushed for 140 yards and a TD, backup kicker Caleb Noe connected on all three of his field-goal attempts and the Bears ended a three-game losing streak while defeating the Patriots for the first time since 2006.
UPike (2-3, 2-1 Mid-South Conference) held No. 23 Cumberlands (0-2, 1-3) to its lowest point total of the season. The seven points were the Patriots' fewest in a game since a 38-7 loss to St. Xavier (Ill.) in the 2010 NAIA playoffs.
Pikeville also handed Cumberlands its first home loss since 2011.
Aaron Jackson, a sophomore transfer from Western Kentucky, led the Bears with 121 yards on five catches.
R.J. Rosemond Jr. went 11-for-28 for 191 yards. He also rushed for 49 yards and a TD.
Faulkner 28, Lindsey Wilson 17: The No. 4 Eagles bested the visiting No. 17 Blue Raiders on Rob Lackhart's 24-yard TD reception with 5 minutes left in the game.