Host Pittsburgh scored the first 19 points only to lose the lead, then came back behind Nasir Robinson's 21 points to hand No. 3 Syracuse its first loss Monday night, with a 74-66 victory in a game of remarkable runs.
Brad Wanamaker added 15 points to help the fifth-ranked Panthers (18-1) improve to 6-0 in the Big East for the first time and halt a long Syracuse winning streak for the second successive season.
The Orange (18-1, 5-1), playing without leading scorer Kris Joseph after he sustained a concussion Saturday against Cincinnati, couldn't match the 1999-2000 team's school record by winning its first 19 games. Syracuse won its first 13 last season, only to lose to Pitt 82-72 at the Carrier Dome.
C.J. Fair had 16 points and nine rebounds for Syracuse, which rallied from the terrible start with a 17-0 run that helped tie the score at 41 with 13:46 remaining. But Pitt scored nine of the next 12 points.
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No. 8 Connecticut 61, No. 7 Villanova 59: Kemba Walker hit a drive down the lane with 2.5 seconds to play to lift host Connecticut (15-2, 4-2 Big East), snapping the Wildcats' 11-game winning streak.
Walker, who entered the game as the nation's second-leading scorer with a 25.6 average, finished with 24 points on a season-worst 6-for-18 from the field. Although he struggled against Villanova's aggressive man-to-man defense, the junior guard scored the Huskies' last seven points.
Corey Fisher, who led Villanova (16-2, 4-1) with 28 points, tied the game at 59 with two free throws with 22 seconds left.
Campbellsville 75, Life 74 (OT): Adrian Whelan, fouled on a three-point attempt with 1.4 seconds to play, made all three free throws to give host Campbellsville (11-7) the victory in overtime. Whelan was 2-for-2 from beyond the arc in overtime and finished with 12 points.
Shawn Savage led Campbellsville with six threes and a career-high 27 points. Campbellsville's JaVaughn Espritt sent the game to overtime at 63-63 with a layup in the final seconds of regulation.
Southern Indiana 93, Kentucky Wesleyan 64: Host Southern Indiana went 11-for-18 from three-point range and routed Kentucky Wesleyan in a Great Lakes Valley College game. Anthony Yopung had 16 points and nine rebounds for Kentucky Wesleyan (12-3, 5-3). SIU (16-1, 8-1) is ranked No. 6 in Division II.
UK's Pinkett honored
Kentucky's Bernisha Pinkett was named the Southeastern Conference's Freshman of the Week on Monday. Pinkett, a 5-foot-7 reserve guard, averaged 15.5 points, 3.5 assists and 2.5 rebounds in wins over South Carolina and Mississippi State.
G-town coach to retire
Georgetown College announced that women's basketball coach Susan Johnson will retire at the end of the season after 32 years at the helm. Johnson is 578-363 at Georgetown, a 61.4 winning percentage. She has taken the Tigers to 11 NAIA national tournaments, including seven in a row, and three Elite Eights.
Southern Illinois-Edwardsville 61, Eastern Kentucky 60: Reese Bass' shot at the buzzer bounced off the rim, and host SIU-Edwardsville (5-12) hung on to beat EKU (4-13).
After Courtney Kenner made two free throws to give SIU-Edwardsville a one-point lead with 7.6 seconds left, the Lady Colonels drove the length of the floor and got the ball to Bass, whose shot from just inside the three-point line bounced off as time expired.
EKU trailed 55-47 with 6:39 left before rallying to take a 60-59 lead with 31 seconds left on two free throws by Alex Jones, who had a team-high 19 points. Henry Clay graduate Brittany Coles added 18 points.
Southern Indiana 85, Kentucky Wesleyan 68: Kentucky Wesleyan failed to hold a seven-point lead in the first half and lost at Southern Indiana. Kourtney Rhoads led Kentucky Wesleyan (9-6, 3-5 GLVC) with 14 points. Amie Newhart had five three-pointers and 27 points for Southern Indiana (10-7, 6-3).
Around the nation
Auburn: Guard Frankie Sullivan will miss the rest of the season because of a knee injury sustained during the summer.
Indiana: Sophomore guard Maurice Creek will be out indefinitely after being diagnosed with a stress fracture in his right kneecap, Coach Tom Crean said Monday night. Creek fractured his other kneecap last season.